Houston Favored Over Florida in 2025 Men’s March Madness Odds

The NCAA Tournament has nearly reached its conclusion.

The UConn Huskies won it in 2024, their second consecutive national title — but they were eliminated in the Round of 32. 

Yes, we will have a new champion.

Let’s check out the odds to win Monday’s National Championship Game at DraftKings Sportsbook as of April 6.

NCAA Men’s Tournament Winner 2025 odds

Florida vs. Houston

Spread: Houston -1
Moneyline: Houston -115, Florida -105
O/U total: 141.5

A program has not three-peated since John Wooden’s UCLA Bruins won six in a row from 1967 to 1973, and that streak will stand.

Duke, Auburn, Florida, and Houston entered the Tournament as the four No. 1 seeds, and all four made up the Final Four, making it only the second time in NCAA Tournament history that all four 1-seeds made it to the national semifinals.

This version of the Tournament has been notable due to its lack of major upsets. For the first time since 2007, there were no teams seeded 11 or lower participating in the Sweet 16, with 10-seed Arkansas representing the lowest seed remaining at that time. 

On Saturday, Florida got past Auburn and Houston edged Duke in an instant classic. 

The Cougars are 1-point favorites over the Gators in the national title game.

Who are you backing to win next year’s NCAA men’s title? Follow FOX Sports for the latest!