The eye-catching entry list was announced by the USTA on Tuesday.
Lew Sherr, the USTA’s chief executive, said the tournament was always “confident” of getting the world’s leading players involved.
“Seeing the teams that have already put their names on the entry list makes us all incredibly excited,” he said.
“It shows that the players are behind what we are trying to do, and we know that the fans will love it.”
The plan received strong criticism from some doubles players when it was announced in February.
Italian pair Sara Errani and Andrea Vavassori, who won last year’s US Open mixed doubles title, are on the entry list, having initially described the decision as a “profound injustice”.
France’s Kristina Mladenovic, winner of multiple Slam doubles titles, said the decision was “terribly shocking”.